Depending when you leave in March and Depending if there is a early summer (or a late winter)
In the Azores the Winter prevailing winds are Westerlies changing from SW to NW - While the Summer winds are Easterlies changing from NE to SE
So, say you leave from Los Palmas on Gran Canaria on a hdg of 318 to Ponto Delgado on Sao Miguel a 1,000 miles away - if there are still westerlies you may be able to sail for part of the day.
if the summer winds are early you will probably have a good sail. Therefore the later you can leave the better - how about May?